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Enhanced Y1-receptor-mediated vasoconstrictive action of neuropeptide Y (NPY) in superior mesenteric arteries in portal hypertension

Wiest, Reiner, Jurzik, Lars, Moleda, Lukas, Froh, Matthias, Schnabl, Bernd, Hörsten, Stephan von, Schölmerich, Juergen and Straub, Rainer H. (2006) Enhanced Y1-receptor-mediated vasoconstrictive action of neuropeptide Y (NPY) in superior mesenteric arteries in portal hypertension. Journal of hepatology 44 (3), pp. 512-519.

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Date of publication of this fulltext: 05 Aug 2009 13:24

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Other URL: http://dx.doi.org/10.1016/j.jhep.2005.08.023


Abstract

BACKGROUND/AIMS: Vascular hyporeactivity to catecholamines contributes to arterial vasodilation and hemodynamic dysregulation in portal hypertension. Neuropeptide Y (NPY) is a sympathetic neurotransmitter facilitating adrenergic vasoconstriction via Y1-receptors on the vascular smooth muscle. Therefore, we investigated its role for vascular reactivity in the superior mesenteric artery (SMA) of ...

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Item type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1016/j.jhep.2005.08.023DOI
16324766PubMed ID
Keywords:Portal hypertension; Splanchnic circulation; Neuropeptide Y; Vasodilation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:798
Owner only: item control page

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