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Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer

Dietmaier, Wolfgang, Bettstetter, Marcus, Wild, Peter J., Woenckhaus, Matthias, Rümmele, Petra, Hartmann, Arndt, Dechant, Stefan, Blaszyk, Hagen, Pauer, Armin, Klinkhammer-Schalke, Monika and Hofstädter, Ferdinand (2006) Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer. International journal of cancer. Journal international du cancer 118 (9), pp. 2247-2254.

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Date of publication of this fulltext: 05 Aug 2009 13:24

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Other URL: http://dx.doi.org/10.1002/ijc.21620


Abstract

Maspin, a member of the Serpin protease inhibitor family, is overexpressed in poorly differentiated colorectal tumors and more frequently found in tumors with microsatellite instability. Immunohistochemical nuclear Maspin staining is predominantly seen in tumor cells at the invasion front of such cancers, suggesting that this molecule is associated with local tumor cell infiltration and ...

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Item type:Article
Date:1 May 2006
Institutions:Medicine > Lehrstuhl für Chirurgie
Identification Number:
ValueType
16331619PubMed ID
10.1002/ijc.21620DOI
Keywords:colon cancer; Maspin; prediction; 5-flourouracil; chemotherapy
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:799
Owner only: item control page

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