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Study of the in vitro penetration of the topical glucocorticoid betamethasone-17-valerate from solution-type gels into a multilayer membrane system.

Bendas, Barbara, Göpferich, Achim, Lee, Geoffrey and Neubert, R. (1993) Study of the in vitro penetration of the topical glucocorticoid betamethasone-17-valerate from solution-type gels into a multilayer membrane system. Die Pharmazie 48 (3), pp. 199-201.

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Abstract

The in vitro transport of betamethasone-17-valerate (1) into a multilayer membrane system has been investigated. Subsaturated formulations of 1 were studied as formed by mixing appropriate propylene glycol/water cosolvent systems. The AUC (drug concentration in acce ptor membrane as a function of time) and the diffusivity of the drug in the vehicle were used to evaluate the results of the in ...

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Item type:Article
Date:1993
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Identification Number:
ValueType
8493284PubMed ID
Classification:
NotationType
Betamethasone 17-Valerate/chemistryMESH
Chemistry, PhysicalMESH
GelsMESH
Membranes, ArtificialMESH
Physicochemical PhenomenaMESH
SolutionsMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:8488
Owner only: item control page

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