Drug delivery from bioerodible polymers: systemic and intravenous administration

URN to cite this document:: urn:nbn:de:bvb:355-epub-85155

Göpferich, Achim ; Gref, Ruxandra ; Minamitake, Yoshiharu ; Shieh, Lisa ; Alonso, Maria Jose ; Tabata, Yashuhiko ; Langer, Robert S.

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Date of publication of this fulltext: 14 Aug 2009 10:32

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Item type:	Book section
ISBN:	0-8412-2959-7
Title of Book:	Formulation and delivery of proteins and peptides
Publisher:	American Chemical Soc.
Place of Publication:	Washington, DC
Other Series:	ACS symposium series
Volume:	567
Page Range:	pp. 242-277
Date:	1994
Institutions:	Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Dewey Decimal Classification:	500 Science > 570 Life sciences 600 Technology > 610 Medical sciences Medicine
Status:	Published
Refereed:	Yes, this version has been refereed
Created at the University of Regensburg:	No
Item ID:	8515

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Abstract

The recent progress in understanding the erosion of biodegradable polymers and the manufacturing of controlled release devices for proteins and peptides is reported. The erosion mechanism of poly(anhydrides) was investigated as an example of biodegradable polymers and the erosion behavior is modeled mathematically. The results provide useful information on the microstructure and chemical ...

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