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Drug delivery from bioerodible polymers: systemic and intravenous administration

URN to cite this document:
urn:nbn:de:bvb:355-epub-85155
Göpferich, Achim ; Gref, Ruxandra ; Minamitake, Yoshiharu ; Shieh, Lisa ; Alonso, Maria Jose ; Tabata, Yashuhiko ; Langer, Robert S.
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Date of publication of this fulltext: 14 Aug 2009 10:32


Abstract

The recent progress in understanding the erosion of biodegradable polymers and the manufacturing of controlled release devices for proteins and peptides is reported. The erosion mechanism of poly(anhydrides) was investigated as an example of biodegradable polymers and the erosion behavior is modeled mathematically. The results provide useful information on the microstructure and chemical ...

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