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Coincidence of increased soluble interleukin-2 receptors, diminished natural killer cell activity and progressive disease in cutaneous T-cell lymphomas

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Dummer, Reinhard ; Nestle, Frank ; Wiede, Johannes ; Schäfer, Erwin ; Röger, Jürgen ; Becker, Jürgen C. ; Vogt, Thomas ; Burg, Günter
Date of publication of this fulltext: 24 Aug 2009 14:31


In 24 patients with cutaneous T-cell lymphomas (CTCL) the clinical course was documented by determination of a tumour burden index (TBI) on entering the study and six months later. In addition to the first TBI, soluble interleukin-2 receptor levels (slL-2R) in the serum were determined using an ELISA technique in 23 patients. In 18 patients natural killer cell (NK) activity was assessed by a 4 h ...


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