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Regulation of surface CD163 expression and cellular effects of receptor mediated hemoglobin-haptoglobin uptake on human monocytes and macrophages

Ugocsai, Peter and Barlage, Stefan and Dada, Ashraf and Schmitz, Gerd (2006) Regulation of surface CD163 expression and cellular effects of receptor mediated hemoglobin-haptoglobin uptake on human monocytes and macrophages. Cytometry. Part A : the journal of the International Society for Analytical Cytology 69 (3), pp. 203-205.

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Other URL: http://dx.doi.org/10.1002/cyto.a.20235


Abstract

Local dysregulation of iron metabolism is suggested to contribute to atherosclerotic lesion development through hemoglobin scavenging pathways. We evaluated the effects of CD163-mediated uptake of hemoglobin-haptoglobin (HbHp) complexes on surface CD163 and intracellular heme oxygenase-1 expression and the secretion of pro- and antiinflammatory cytokines by macrophages. We found that increased ...

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Item Type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Identification Number:
ValueType
16479607PubMed ID
10.1002/cyto.a.20235DOI
Keywords:CD163; heme oxygenase-1; inflammatory cytokines
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Ute Lange
Deposited On:08 Feb 2007
Last Modified:13 Mar 2014 09:44
Item ID:1025
Owner Only: item control page

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