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Establishment of functional cannabinoid receptor test systems and evaluation of ligands derived from Echinacea pallida

URN to cite this document: urn:nbn:de:bvb:355-opus-9892

Nickl, Kathrin (2008) Establishment of functional cannabinoid receptor test systems and evaluation of ligands derived from Echinacea pallida. PhD, Universität Regensburg

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Abstract (English)

Cannabinoid receptors (CBRs) have been of high interest since their discovery in the early 1990s. Until now, two different subtypes, the human cannabinoid receptor 1 (hCB1R) and the human cannabinoid receptor 2 (hCB2R) are known. Both regulate important body functions, such as appetite, motor coordination, inflammation and host defence. Identifying new ligands at CBRs is of high importance for ...

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Translation of the abstract (German)

Seit ihrer Entdeckung in den frühen 1990er Jahren war das wissenschaftliche Interesse an Cannabinoid-Rezeptoren (CBR) groß. Zur Zeit sind zwei verschiedene Subtypen, der humane Cannabinoid-Rezeptor 1 (hCB1R) und der humane Cannabinoid-Rezeptor 2 (hCB2R) bekannt. Beide Rezeptoren regulieren wichtige Körperfunktionen, z. B. Appetit, Motorik, Entzündungen und Immunabwehr. CBR-Liganden sind als ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:17 June 2008
Referee:Jörg (Prof. Dr.) Heilmann
Date of exam:23 May 2008
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Keywords:Cannabinoide , Rezeptor , Ligand <Biochemie> , Pharmakologie , Blassfarbener Igelkopf , GTPase-Assay , GTPgammaS-Assay , Kopplung , G-Protein , Testsystem , GPCR , Cannabinoidrezeptor , Echinacea , Alkamide , THC , GTPase assay , GTPgammaS assay , coupling , G-protein
Subjects:500 Science
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:27 Oct 2009 16:25
Last Modified:13 Mar 2014 11:54
Item ID:10750
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