Kunz-Schughart, Leoni A. and Schroeder, Josef A. and Wondrak, Marit and Rey, Frank van and Lehle, Karla and Hofstaedter, Ferdinand and Wheatley, Denys N. (2006) Potential of fibroblasts to regulate the formation of three-dimensional vessel-like structures from endothelial cells in vitro. American journal of physiology. Cell physiology 290 (5), C1385-C1398.
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Other URL: http://dx.doi.org/10.1152/ajpcell.00248.2005
The development of vessel-like structures in vitro to mimic as well as to realize the possibility of tissue-engineered small vascular networks presents a major challenge to cell biologists and biotechnologists. We aimed to establish a three-dimensional (3-D) culture system with an endothelial network that does not require artificial substrates or ECM compounds. By using human skin fibroblasts and ...
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|Institutions:||Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie|
|Keywords:||endothelium; angiogenesis; human umbilical vein endothelial cell; multicellular spheroid; coculture; tubular structures|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||02 Mar 2007|
|Last Modified:||13 Mar 2014 09:46|