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Potential of fibroblasts to regulate the formation of three-dimensional vessel-like structures from endothelial cells in vitro

Kunz-Schughart, Leoni A. and Schroeder, Josef A. and Wondrak, Marit and Rey, Frank van and Lehle, Karla and Hofstaedter, Ferdinand and Wheatley, Denys N. (2006) Potential of fibroblasts to regulate the formation of three-dimensional vessel-like structures from endothelial cells in vitro. American journal of physiology. Cell physiology 290 (5), C1385-C1398.

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Other URL: http://dx.doi.org/10.1152/ajpcell.00248.2005


Abstract

The development of vessel-like structures in vitro to mimic as well as to realize the possibility of tissue-engineered small vascular networks presents a major challenge to cell biologists and biotechnologists. We aimed to establish a three-dimensional (3-D) culture system with an endothelial network that does not require artificial substrates or ECM compounds. By using human skin fibroblasts and ...

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Item Type:Article
Date:May 2006
Institutions:Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Identification Number:
ValueType
10.1152/ajpcell.00248.2005DOI
16601149PubMed ID
Keywords:endothelium; angiogenesis; human umbilical vein endothelial cell; multicellular spheroid; coculture; tubular structures
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:02 Mar 2007
Last Modified:13 Mar 2014 09:46
Item ID:1211
Owner Only: item control page
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