URN to cite this document: urn:nbn:de:bvb:355-epub-124128
Meier, Johannes (2010) Die unterschiedlichen Migrationspotentiale von Myofibroblasten aus entzündeter, fistulierter und stenosierter Darmschleimhaut von Morbus-Crohn-Patienten gehen mit einer unterschiedlichen Expression der Focal Adhesion Kinase (FAK) einher. PhD, Universität Regensburg
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Abstract (German)
Im 3D-Matrixmodell konnte gezeigt werden, dass sich Myofibroblasten aus entzündeter, fistulierter und stenosierter Darmschleimhaut von Morbus Crohn Patienten hinsichtlich Ihrer Migrationspotentiale voneinander unterscheiden. Dies geht ausserdem mit einer unterschiedlichen Expression der Focal Adhesion Kinase (FAK) einher.
Translation of the abstract (English)
Myofibroblasts isolated from inflamed, fibrostenotic or fistulized CD mucosa differ in their migratory potential both in the modified Boyden chamber as well as in a 3D-matrix model. These different migratory behaviours are associated with a different expression of FAK.
| Item Type: | Thesis of the University of Regensburg (PhD) |
|---|---|
| Referee: | Prof. Dr. Dr. Gerhard Rogler and Prof. Dr. Dr. Torsten E. Reichert |
| Date of exam: | 21 January 2010 |
| Institutions: | Medicine > Lehrstuhl für Innere Medizin I |
| Keywords: | Crohn’s disease, fibrosis, strictures, myofibroblasts, migration, wound healing, focal adhesion kinase |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Status: | Published |
| Refereed: | Yes, this version has been refereed |
| Created at the University of Regensburg: | Yes |
| Owner: | Universitätsbibliothek Regensburg |
| Deposited On: | 18 Feb 2010 15:24 |
| Last Modified: | 21 Jul 2011 00:17 |
| Item ID: | 12412 |
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