Goppelt-Struebe, M. and Hahn, A. and Iwanciw, D. and Rehm, M. and Banas, B. (2001) Regulation of connective tissue growth factor (ccn2; ctgf) gene expression in human mesangial cells: modulation by HMG CoA reductase inhibitors (statins). Molecular pathology: MP 54 (3), pp. 176-179.
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AIM: Connective tissue growth factor (ccn; ctgf) gene expression is upregulated in fibrotic renal glomeruli. Therefore, the regulation and pharmacological modulation of ccn2 (ctgf) mRNA expression was investigated in a human renal mesangial cell line. METHODS: A human renal mesangial cell line was cultured in vitro under standard conditions. After stimulation, RNA was extracted and ccn2 (ctgf) ...
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|Institutions:||Medicine > Lehrstuhl für Innere Medizin II|
|Keywords:||connective tissue growth factor; ccn2; Rho proteins; statins; mesangial cells|
|Dewey Decimal Classification:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||No|
|Deposited on:||09 Mar 2007|
|Last modified:||13 Mar 2014 09:48|