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Regulation of connective tissue growth factor (ccn2; ctgf) gene expression in human mesangial cells: modulation by HMG CoA reductase inhibitors (statins)

Goppelt-Struebe, M. and Hahn, A. and Iwanciw, D. and Rehm, M. and Banas, B. (2001) Regulation of connective tissue growth factor (ccn2; ctgf) gene expression in human mesangial cells: modulation by HMG CoA reductase inhibitors (statins). Molecular pathology: MP 54 (3), pp. 176-179.

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Abstract

AIM: Connective tissue growth factor (ccn; ctgf) gene expression is upregulated in fibrotic renal glomeruli. Therefore, the regulation and pharmacological modulation of ccn2 (ctgf) mRNA expression was investigated in a human renal mesangial cell line. METHODS: A human renal mesangial cell line was cultured in vitro under standard conditions. After stimulation, RNA was extracted and ccn2 (ctgf) ...

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Item Type:Article
Date:June 2001
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
11376131PubMed ID
Keywords:connective tissue growth factor; ccn2; Rho proteins; statins; mesangial cells
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Petra Gürster
Deposited On:09 Mar 2007
Last Modified:13 Mar 2014 09:48
Item ID:1264
Owner Only: item control page

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