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Angiotensin inhibition reduces glomerular damage and renal chemokine expression in MRL/lpr mice

Pérez De Lema, Guillermo and De Wit, Cor and Cohen, Clemens D and Nieto, Elena and Molina, Ana and Banas, Bernhard and Luckow, Bruno and Vicente, Ana B and Mampaso, Francisco and Schlöndorff, Detlef (2003) Angiotensin inhibition reduces glomerular damage and renal chemokine expression in MRL/lpr mice. The Journal of pharmacology and experimental therapeutics 307 (1), pp. 275-281.

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Abstract

Beneficial effects of angiotensin II inhibition during inflammatory renal disease may involve both hemodynamic and nonhemodynamic mechanisms. To analyze whether angiotensin II inhibition has protective effects on lupus-like, autoimmune-mediated renal damage in MRL/lpr mice, four groups of mice were treated orally for 6 weeks with: 1) vehicle, 2) enalapril (3.0 mg/kg per day), 3) candesartan ...

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Item Type:Article
Date:October 2003
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
10.1124/jpet.103.053678DOI
12954793PubMed ID
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Petra Gürster
Deposited On:13 Mar 2007
Last Modified:13 Mar 2014 09:48
Item ID:1276
Owner Only: item control page

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