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Localization and functional characterization of glycosaminoglycan domains in the normal human kidney as revealed by phage display-derived single chain antibodies

Lensen, Joost F. M. and Rops, Angelique L. W. M. M. and Wijnhoven, Tessa J. M. and Hafmans, Theo and Feitz, Wouter F. J. and Oosterwijk, Egbert and Banas, Bernhard and Bindels, René J. M. and van den Heuvel, Lambert P. W. J. and van der Vlag, Johan and Berden, Jo H. M. and van Kuppevelt, Toin H. (2005) Localization and functional characterization of glycosaminoglycan domains in the normal human kidney as revealed by phage display-derived single chain antibodies. Journal of the American Society of Nephrology: JASN 16 (5), pp. 1279-1288.

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Other URL: http://dx.doi.org/10.1681/ASN.2004050413


Abstract

Glycosaminoglycans (GAG) play an important role in renal homeostasis. They are strongly negatively charged polysaccharides that bind and modulate a myriad of proteins, including growth factors, cytokines, and enzymes. With the aid of specific phage display-derived antibodies, the distribution of heparan sulfate (HS) and chondroitin sulfate (CS) domains in the normal human kidney was studied. HS ...

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Item Type:Article
Date:May 2005
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
15788473PubMed ID
10.1681/ASN.2004050413DOI
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Petra Gürster
Deposited On:16 Mar 2007
Last Modified:13 Mar 2014 09:49
Item ID:1300
Owner Only: item control page

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