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Novel role of toll-like receptor 3 in hepatitis C-associated glomerulonephritis

Wörnle, Markus and Schmid, Holger and Banas, Bernhard and Merkle, Monika and Henger, Anna and Roeder, Maximilian and Blattner, Simone and Bock, Elisabeth and Kretzler, Matthias and Gröne, Hermann-Josef and Schlöndorff, Detlef (2006) Novel role of toll-like receptor 3 in hepatitis C-associated glomerulonephritis. The American journal of pathology 168 (2), pp. 370-385.

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Other URL: DOI:10.2353/ajpath.2006.050491


Abstract

Hepatitis C virus (HCV) infection is frequently complicated by glomerulonephritis with immune complexes containing viral RNA. We examined the potential influence of Toll-like receptors (TLRs), specifically TLR3 recognition of viral dsRNA exemplified by polyriboinosinic:polyribocytidylic acid [poly(I:C) RNA]. Normal human kidney stained positive for TLR3 on mesangial cells (MCs), vascular smooth ...

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Item Type:Article
Date:February 2006
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
16436653PubMed ID
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Petra Gürster
Deposited On:20 Mar 2007
Last Modified:13 Mar 2014 09:50
Item ID:1311
Owner Only: item control page
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