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Synthesis of conformationally restricted amino acids and their use in the preparation of biologically active peptides and peptidomimetics

URN to cite this document: urn:nbn:de:bvb:355-epub-133899

Cattaneo, Cristian (2010) Synthesis of conformationally restricted amino acids and their use in the preparation of biologically active peptides and peptidomimetics. PhD, Universität Regensburg

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Abstract (English)

A very efficiently synthetic strategy was developed aiming to obtain a series of amino acids containing the rigid azabicyclo[3.2.1]octane scaffold in few steps, multi gram scale, and starting from commercially available compounds. Furthermore, enantiomerically pure azabicyclo[3.2.1]octane amino acids were also prepared using a very efficient protocol consisting in the use of an asymmetric ...

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Translation of the abstract (German)

Es wurde eine sehr effiziente Synthesestrategie mit dem Ziel entwickelt, eine Reihe von Aminosäuren, die das starre Azabicyclo[3.2.1]octan-Gerüst enthalten, in wenigen Stufen, im Multigramm-Maßstab, sowie unter der Verwendung kommerziell erhältlicher Ausgangsverbindungen, herzustellen. Desweiteren wurden auch enantiomerenreine Azabicyclo[3.2.1]octan-Aminosäuren nach einer sehr effektiven ...

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Export bibliographical data

Item Type:Thesis of the University of Regensburg (PhD)
Date:17 May 2010
Referee:Prof. Dr. Oliver Reiser and Prof. Dr. Maria Luisa Gelmi
Date of exam:11 December 2008
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Keywords:unnatürlich, Aminosäure, Synthese, Anwendung, unnatural, aminoacid, synthesis, applications, constrained
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:17 May 2010 07:31
Last Modified:13 Mar 2014 13:18
Item ID:13389
Owner Only: item control page
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