Dietmaier, Wolfgang and Bettstetter, Marcus and Wild, Peter J. and Woenckhaus, Matthias and Rümmele, Petra and Hartmann, Arndt and Dechant, Stefan and Blaszyk, Hagen and Pauer, Armin and Klinkhammer-Schalke, Monika and Hofstädter, Ferdinand (2006) Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer. International journal of cancer. Journal international du cancer 118 (9), pp. 2247-2254.
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Other URL: http://dx.doi.org/10.1002/ijc.21620
Maspin, a member of the Serpin protease inhibitor family, is overexpressed in poorly differentiated colorectal tumors and more frequently found in tumors with microsatellite instability. Immunohistochemical nuclear Maspin staining is predominantly seen in tumor cells at the invasion front of such cancers, suggesting that this molecule is associated with local tumor cell infiltration and ...
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|Date:||1 May 2006|
|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Keywords:||colon cancer; Maspin; prediction; 5-flourouracil; chemotherapy|
|Dewey Decimal Classification:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited on:||31 Mar 2010 09:18|
|Last modified:||31 Mar 2010 09:18|