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Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer

Dietmaier, Wolfgang and Bettstetter, Marcus and Wild, Peter J. and Woenckhaus, Matthias and Rümmele, Petra and Hartmann, Arndt and Dechant, Stefan and Blaszyk, Hagen and Pauer, Armin and Klinkhammer-Schalke, Monika and Hofstädter, Ferdinand (2006) Nuclear Maspin expression is associated with response to adjuvant 5-fluorouracil based chemotherapy in patients with stage III colon cancer. International journal of cancer. Journal international du cancer 118 (9), pp. 2247-2254.

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Other URL: http://dx.doi.org/10.1002/ijc.21620


Abstract

Maspin, a member of the Serpin protease inhibitor family, is overexpressed in poorly differentiated colorectal tumors and more frequently found in tumors with microsatellite instability. Immunohistochemical nuclear Maspin staining is predominantly seen in tumor cells at the invasion front of such cancers, suggesting that this molecule is associated with local tumor cell infiltration and ...

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Item Type:Article
Date:1 May 2006
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
16331619PubMed ID
10.1002/ijc.21620DOI
Keywords:colon cancer; Maspin; prediction; 5-flourouracil; chemotherapy
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:31 Mar 2010 09:18
Last Modified:31 Mar 2010 09:18
Item ID:13956
Owner Only: item control page
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