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Alkyl-lysophospholipid induced suppression of human lymphocyte response to mitogens and selective killing of lymphoblasts

Andreesen, Reinhard and Modolell, M. and Weltzien, H. U. and Munder, P. G. (1980) Alkyl-lysophospholipid induced suppression of human lymphocyte response to mitogens and selective killing of lymphoblasts. Immunobiology 156 (4-5), pp. 498-508.

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Abstract

Alkyl-analogs of 2-lysophosphatidylcholine have been found to inhibit the response of human peripheral blood lymphocytes to mitogens and allogeneic cells. Furthermore, these compounds kill selectively transformed lymphocytes in vitro while resting lymphocytes are not affected in their viability. The increased incorporation of fatty acids into cellular phospholipids during lymphocyte stimulation ...

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Item Type:Article
Date:1980
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
6445326PubMed ID
Classification:
NotationType
Concanavalin A/pharmacologyMESH
Cytotoxicity, ImmunologicMESH
Dose-Response Relationship, ImmunologicMESH
HumansMESH
ImmunosuppressionMESH
Linoleic Acids/metabolismMESH
Lymphocyte ActivationMESH
Lymphocyte Culture Test, MixedMESH
Lymphocytes/metabolismMESH
Lysophosphatidylcholines/pharmacologyMESH
Mitogens/pharmacologyMESH
Phospholipids/metabolismMESH
Phytohemagglutinins/pharmacologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:13 Apr 2010 05:13
Last Modified:13 Apr 2010 05:13
Item ID:14159
Owner Only: item control page
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