Modolell, M. and Andreesen, Reinhard and Pahlke, W. and Brugger, U. and Munder, P. G. (1979) Disturbance of phospholipid metabolism during the selective destruction of tumor cells induced by alkyl-lysophospholipids. Cancer research 39 (11), pp. 4681-6.
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Alkyl-lysophospholipids inhibit the growth of Meth A sarcoma cells in vitro. In contrast, murine bone marrow macrophages are not sensitive to the destructive effect of these substances. Since alkyl-lysophospholipids are antimetabolites in the synthesis of 3-sn-phosphatidylcholine, tumor cell destruction can be correlated with the disturbance of this metabolism. A decreased synthesis of ...
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|Institutions:||Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)|
|Dewey Decimal Classification:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited on:||13 Apr 2010 05:14|
|Last modified:||13 Apr 2010 05:14|