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Biological response to intravenously administered endotoxin in patients with advanced cancer

Engelhardt, R. and Mackensen, A. and Galanos, C. and Andreesen, Reinhard (1990) Biological response to intravenously administered endotoxin in patients with advanced cancer. Journal of biological response modifiers 9 (5), pp. 480-91.

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Abstract

The purpose of the study was to evaluate the toxicity and biological activity of highly purified lipopolysaccharide (LPS) administered intravenously to cancer patients in order to establish an optimum dosage scheme. An initial subtoxic dose was increased in weekly increments in accordance with individual regimens that maintained patient reaction at a safe and acceptable level. Purified LPS from ...

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Item Type:Article
Date:1990
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
2254760PubMed ID
Classification:
NotationType
AdultMESH
AgedMESH
C-Reactive Protein/analysisMESH
FemaleMESH
Hematologic TestsMESH
HumansMESH
Ibuprofen/therapeutic useMESH
Injections, IntravenousMESH
Interleukin-1/bloodMESH
Interleukin-6/bloodMESH
Lipopolysaccharides/toxicityMESH
MaleMESH
Middle AgedMESH
Neoplasms/therapyMESH
Tachyphylaxis/physiologyMESH
Tumor Necrosis Factor-alpha/analysisMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:39
Last Modified:14 Apr 2010 05:39
Item ID:14254
Owner Only: item control page
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