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Phagocytosis of nanoparticles by human immunodeficiency virus (HIV)-infected macrophages: a possibility for antiviral drug targeting

Schäfer, V. and von Briesen, H. and Andreesen, Reinhard and Steffan, A. M. and Royer, C. and Tröster, S. and Kreuter, J. and Rübsamen-Waigmann, H. (1992) Phagocytosis of nanoparticles by human immunodeficiency virus (HIV)-infected macrophages: a possibility for antiviral drug targeting. Pharmaceutical research 9 (4), pp. 541-6.

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Abstract

Human monocytes/macrophages (MO/MAC) were isolated from peripheral blood and cultivated on hydrophobic Teflon membranes. This culture system is suitable for HIV infection of MO/MAC in vitro. After transfer into 24-well plates the mature macrophages (infected or uninfected) were used for measurements of phagocytosis. The uptake of different, radioactively labeled nanoparticles (NP) made of ...

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Item Type:Article
Date:1992
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
1495900PubMed ID
Classification:
NotationType
Antiviral Agents/pharmacologyMESH
Cells, CulturedMESH
HIV/metabolismMESH
HumansMESH
Macrophages/microbiologyMESH
Microscopy, Electron, ScanningMESH
PhagocytosisMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Apr 2010 05:22
Last Modified:14 Apr 2010 05:22
Item ID:14273
Owner Only: item control page
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