Konur, A. and Kreutz, M. and Knüchel, R. and Krause, S. W. and Andreesen, Reinhard (1996) Three-dimensional co-culture of human monocytes and macrophages with tumor cells: analysis of macrophage differentiation and activation. International journal of cancer. Journal international du cancer 66 (5), pp. 645-52.
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Here we report on an experimental system for generating TAM in vitro by culturing human MO and MO-derived macrophages (MAC) within 3-dimensional multicellular tumor spheroids (MCS). MO as well as MO-derived MAC migrate into tumor spheroids and spread throughout the entire spheroid within 16 hr. In contrast, fibroblast-spheroids were not infiltrated. The regular expression of MAC ...
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|Institutions:||Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)|
|Dewey Decimal Classification:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||14 Apr 2010 05:00|
|Last Modified:||14 Apr 2010 05:00|