Lübbert, M. and Henschler, R. and Kreutz, M. and Andreesen, Reinhard and Mertelsmann, R. and Herrmann, F. (1997) The human lysozyme gene undergoes stepwise demethylation during phagocyte maturation. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 11 (7), pp. 990-7.
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The lysozyme (LZM) gene provides a very useful model for studies of phagocyte maturation, because its protein synthesis is increased during myelopoiesis and thus most abundant in terminally differentiated and activated phagoyctes. LZM gene expression and DNA methylation were examined in various normal and transformed hematopoietic cells. Two shifts toward LZM gene demethylation coincided with ...
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|Institutions:||Medicine > Abteilung für Hämatologie und Internistische Onkologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||15 Apr 2010 05:38|
|Last Modified:||15 Apr 2010 05:38|