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Retinoic acid inhibits monocyte to macrophage survival and differentiation

Kreutz, M. and Fritsche, J. and Ackermann, U. and Krause, S. W. and Andreesen, Reinhard (1998) Retinoic acid inhibits monocyte to macrophage survival and differentiation. Blood 91 (12), pp. 4796-802.

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Abstract

Vitamin A metabolites are potent differentiation-inducing agents for myelomonocytic cell lines in vitro and are successfully used for the treatment of patients with acute promyelocytic leukemia. However, little is known about the effects of vitamin A on normal hematopoietic cells. Therefore, we investigated the effect of vitamin A on differentiation and activation of human blood monocytes (MO). ...

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Item Type:Article
Date:1998
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
9616179PubMed ID
Classification:
NotationType
Cell Differentiation/drug effectsMESH
Cell Survival/drug effectsMESH
Cells, CulturedMESH
HumansMESH
Keratolytic Agents/pharmacologyMESH
Macrophage Colony-Stimulating Factor/pharmacologyMESH
Macrophages/enzymologyMESH
Metalloendopeptidases/biosynthesisMESH
Monocytes/enzymologyMESH
Tretinoin/pharmacologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2010 05:32
Last Modified:15 Apr 2010 05:32
Item ID:14327
Owner Only: item control page
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