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Genomic organization of the human gene HEP27: alternative promoter usage in HepG2 cells and monocyte-derived dendritic cells

Heinz, Sven and Krause, Stefan W and Gabrielli, Franco and Wagner, Harald M and Andreesen, Reinhard and Rehli, Michael (2002) Genomic organization of the human gene HEP27: alternative promoter usage in HepG2 cells and monocyte-derived dendritic cells. Genomics 79 (4), pp. 608-15.

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Abstract

We used representational difference analysis to discover new genes with specific expression in dendritic cells. Among other genes, we identified HEP27, encoding a member of the short chain alcohol dehydrogenase/reductase family to be upregulated during monocyte to dendritic cell differentiation. Originally cloned from hepatocellular carcinoma cells (HepG2), HEP27 was exclusively expressed in ...

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Item Type:Article
Date:2002
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
11944995PubMed ID
10.1006/geno.2002.6743DOI
Classification:
NotationType
Alcohol Dehydrogenase/geneticsMESH
Alcohol OxidoreductasesMESH
Alternative Splicing/geneticsMESH
Base SequenceMESH
Butyrates/pharmacologyMESH
Cells, CulturedMESH
Dendritic Cells/metabolismMESH
Gene Expression Regulation/physiologyMESH
Genome, HumanMESH
HumansMESH
Molecular Sequence DataMESH
Nuclear Proteins/geneticsMESH
Organ SpecificityMESH
Promoter Regions, GeneticMESH
Sequence Analysis, DNAMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2010 05:15
Last Modified:15 Apr 2010 05:15
Item ID:14360
Owner Only: item control page
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