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Activation of lymphocytes inhibits human monocyte to macrophage differentiation

Krause, S. W. and Zaiss, M. and Kreutz, M. and Andreesen, Reinhard (2001) Activation of lymphocytes inhibits human monocyte to macrophage differentiation. Immunobiology 203 (5), pp. 709-24.

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Abstract

Tissue macrophages (MAC) differentiate from circulating blood monocytes (MO) during a maturation step that is of crucial importance for their functional competence. In vitro a similar process of maturation can be observed, if MO are cultured in the presence of serum. In the work presented here, we show that activated lymphocytes can interfere with MAC differentiation. Resting lymphocytes have ...

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Item Type:Article
Date:2001
Institutions:Medicine > Abteilung für Hämatologie und Internistische Onkologie
Identification Number:
ValueType
11563672PubMed ID
Classification:
NotationType
Antigens, CD/analysisMESH
Cell DifferentiationMESH
Cells, CulturedMESH
Concanavalin A/pharmacologyMESH
Culture Media, ConditionedMESH
HumansMESH
Interferon-gamma/pharmacologyMESH
Lymphocyte ActivationMESH
Macrophages/immunologyMESH
Membrane GlycoproteinsMESH
Metalloendopeptidases/analysisMESH
Monocytes/immunologyMESH
Phagocytosis/drug effectsMESH
Pokeweed Mitogens/pharmacologyMESH
Poly I-CMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2010 05:05
Last Modified:15 Apr 2010 05:05
Item ID:14363
Owner Only: item control page
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