Jakse, G. and Rauschmeier, H and Rosmanith, P. and Hofstädter, Ferdinand (1983) Determination of carcinoembryonic antigen in tissue, serum and urine in patients with transitional cell carcinoma of the urinary bladder. Urologia internationalis 38 (3), pp. 121-125.
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Carcinoembryonic antigen (CEA) is elevated in urine and/or serum of patients with transitional cell carcinoma (TCC) of the urinary bladder. A group of 26 patients with TCC of the urinary bladder were evaluated with regard to urine/serum CEA levels and CEA tissue content. CEA could be detected in normal, metaplastic and pre-neoplastic urothelium as well as tumor tissue. CEA was mainly localized on cell membranes, but with increasing tumor malignancy and infiltration a shift to cytoplasmatic localized CEA was noted. There was also a decrease in CEA content in the latter group. CEA urine levels were elevated above normal in more advanced tumor stages; however, the values varied greatly between individuals. All serum levels were within normal limits. No correlation could be established between urine/serum CEA levels and CEA tissue content.
|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||17 May 2010 12:34|
|Last Modified:||17 May 2010 12:34|