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Molecular analysis of microdissected tumors and preneoplastic intraductal lesions in pancreatic carcinoma

Heinmöller, E. and Dietmaier, W. and Zirngibl, H. and Heinmöller, P. and Scaringe, W. and Jauch, K. W. and Hofstädter, Ferdinand and Rüschoff, J. (2000) Molecular analysis of microdissected tumors and preneoplastic intraductal lesions in pancreatic carcinoma. The American journal of pathology 157 (1), pp. 83-92.

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Abstract

Little or no data exist concerning the inactivation of tumor suppressor genes in intraductal lesions surrounding invasive ductal pancreatic carcinomas. Using a novel improved primer extension and preamplification polymerase chain reaction, we analyzed microdissected paraffin-embedded specimens of pancreatic carcinoma (n = 29) and their corresponding pancreatic intraductal lesions (PIL, n = 331) ...

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Item Type:Article
Date:2000
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
8311654PubMed ID
Classification:
NotationType
Carcinoma, Intraductal, Noninfiltrating/pathologyMESH
Cyclin-Dependent Kinase Inhibitor p16/geneticsMESH
DNA-Binding Proteins/geneticsMESH
HumansMESH
ImmunohistochemistryMESH
Loss of HeterozygosityMESH
Microsatellite RepeatsMESH
Neoplasm StagingMESH
Pancreas/pathologyMESH
Pancreatic Neoplasms/pathologyMESH
Precancerous Conditions/pathologyMESH
Smad4 ProteinMESH
Trans-Activators/geneticsMESH
Tumor Suppressor Protein p53/geneticsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:17 Jun 2010 08:13
Last Modified:17 Jun 2010 08:13
Item ID:15366
Owner Only: item control page
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