Dietmaier, W. and Hofstädter, Ferdinand (2001) Detection of microsatellite instability by real time PCR and hybridization probe melting point analysis. Laboratory investigation 81 (10), pp. 1453-1456.
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Microsatellite alterations can be found in a number of tumors. There are two types of alterations: loss of heterozygosity (LOH), which can be detected in the majority of colorectal cancers (CRC), and microsatellite instability (MSI). MSI occurs in about 15% of CRC with a mutator phenotype and are the hallmark of hereditary nonpolyposis colorectal cancers (HNPCC). Furthermore, MSI can also be ...
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|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||18 Jun 2010 08:54|
|Last Modified:||18 Jun 2010 08:54|