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Frequent microsatellite instability in sporadic tumors of the upper urinary tract

Hartmann, Arndt and Zanardo, Livia and Bocker-Edmonston, Tina and Blaszyk, Hagen and Dietmaier, Wolfgang and Stoehr, Robert and Cheville, John C. and Junker, Kerstin and Wieland, Wolf and Knuechel, Ruth and Rueschoff, Josef and Hofstaedter, Ferdinand and Fishel, Richard (2002) Frequent microsatellite instability in sporadic tumors of the upper urinary tract. Cancer research 62 (23), pp. 6796-6802.

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Abstract

Urothelial carcinoma of the renal pelvis and ureter may develop sporadically or as a manifestation of hereditary nonpolyposis colorectal cancer. The majority of hereditary nonpolyposis colorectal cancer is caused by mutation of the human DNA mismatch repair (MMR) genes and is detected by associated microsatellite instability (MSI). Seventy-three unselected urothelial carcinomas of the ureter ...

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Item Type:Article
Date:2002
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
12460887PubMed ID
Classification:
NotationType
Adaptor Proteins, Signal TransducingMESH
AdultMESH
AgedMESH
Aged, 80 and overMESH
Base Pair MismatchMESH
Carrier ProteinsMESH
DNA Repair/geneticsMESH
DNA-Binding Proteins/geneticsMESH
FemaleMESH
Frameshift MutationMESH
HumansMESH
Kidney Neoplasms/pathologyMESH
Kidney Pelvis/pathologyMESH
MaleMESH
Microsatellite Repeats/geneticsMESH
Middle AgedMESH
MutS Homolog 2 ProteinMESH
Neoplasm Proteins/geneticsMESH
Nuclear ProteinsMESH
Protein-Serine-Threonine KinasesMESH
Proto-Oncogene Proteins/geneticsMESH
Proto-Oncogene Proteins c-bcl-2MESH
Receptor, IGF Type 2/geneticsMESH
Receptors, Transforming Growth Factor beta/geneticsMESH
Ureteral Neoplasms/pathologyMESH
bcl-2-Associated X ProteinMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:18 Jun 2010 08:42
Last Modified:18 Jun 2010 08:42
Item ID:15405
Owner Only: item control page
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