Hafner, Christian and López-Knowles, Elena and Luis, Nuno M. and Toll, Agustí and Baselga, Eulàlia and Fernández-Casado, Alex and Hernández, Silvia and Ribé, Adriana and Mentzel, Thomas and Stoehr, Robert and Hofstaedter, Ferdinand and Landthaler, Michael and Vogt, Thomas and Pujol, Ramòn M. and Hartmann, Arndt and Real, Francisco X. (2007) Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern. Proceedings of the National Academy of Sciences of the United States of America: PNAS 104 (33), pp. 13450-13454.
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Activating mutations of the p110 alpha subunit of PI3K (PIK3CA) oncogene have been identified in a broad spectrum of malignant tumors. However, their role in benign or preneoplastic conditions is unknown. Activating FGF receptor 3 (FGFR3) mutations are common in benign skin lesions, either as embryonic mutations in epidermal nevi (EN) or as somatic mutations in seborrheic keratoses (SK). FGFR3 ...
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|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||18 Jun 2010 08:30|
|Last Modified:||18 Jun 2010 08:30|