Esparza, I. and Männel, Daniela N. and Ruppel, A. and Falk, Werner and Krammer, P.H. (1987) Interferon gamma and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni. The Journal of experimental medicine 166 (2), pp. 589-594.
Macrophages play a crucial role in the defense against tumors and parasites. Activation of tumoricidal and microbicidal effector mechanisms requires stimulation of macrophages with macrophage-activating factors (MAF). One such MAF is interferon gamma (IFN-gamma). In some assays, substantial activity of IFN-gamma on murine macrophages, however, is only observed in synergy with lipopolysaccharide ...
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|Institutions:||Medicine > Lehrstuhl für Innere Medizin I|
Medicine > Lehrstuhl für Immunologie
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||21 Jul 2010 09:21|
|Last Modified:||13 Mar 2014 13:54|