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Tumor necrosis factor: a cytokine involved in toxic effects of endotoxin

Männel, Daniela N. and Northoff, H. and Bauss, F. and Falk, Werner (1987) Tumor necrosis factor: a cytokine involved in toxic effects of endotoxin. Reviews of infectious diseases 9 Suppl 5, S602-S606.

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Abstract

Endotoxin-induced tumor necrosis has been shown to be mediated by a factor termed tumor necrosis factor (TNF). The biochemical nature, source, and mode of induction of TNF have been clarified. TNF is a mediator of activated macrophages that is released into the supernatant by these cells after their stimulation with endotoxin. A number of biologic functions of TNF other than its tumoricidal ...

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Item Type:Article
Date:1987
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Medicine > Lehrstuhl für Immunologie
Identification Number:
ValueType
3500495PubMed ID
Related URLs:
URLURL Type
http://www.jstor.org/pss/4454241UNSPECIFIED
Classification:
NotationType
AnimalsMESH
Blood Glucose/analysisMESH
Body Temperature/drug effectsMESH
Endotoxins/toxicityMESH
HematocritMESH
HumansMESH
Interleukin-1/biosynthesisMESH
Lactates/bloodMESH
Lipopolysaccharides/toxicityMESH
Macrophages/drug effectsMESH
MiceMESH
Mice, Inbred C3HMESH
Monocytes/metabolismMESH
Recombinant Proteins/pharmacologyMESH
Tumor Necrosis Factor-alpha/toxicityMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:21 Jul 2010 09:19
Last Modified:16 Jun 2011 06:13
Item ID:15990
Owner Only: item control page
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