Brunner, E. and Arnold, M. R. and Kremer, W. and Kalbitzer, Hans Robert (2001) Pressure-stability of phospholipid bicelles: measurement of residual dipolar couplings under extreme conditions. Journal of biomolecular NMR 21 (2), pp. 173-176.
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High-pressure NMR of proteins in solutions currently gains increasing interest. 3D structure determination of proteins under high pressure is, however, so far impossible due to the lack of NOE information. Residual dipolar couplings induced by the addition of magnetically orienting media are known to be capable of replacing NOE information to a very high extent. In the present contribution we study the pressure-stability of dimyristoylphosphatidylcholine (DMPC)/dihexanoylphosphatidylcholine (DHPC) bicelles and demonstrate the feasibility of measuring residual dipolar couplings in proteins under high pressure.
|Institutions:||Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Dr. Hans Robert Kalbitzer|
|Subjects:||500 Science > 570 Life sciences|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||09 Sep 2010 07:15|
|Last Modified:||09 Sep 2010 07:15|