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Bioactive natural products from the Popoluca Indian medicinal plant Mosquitoxylum jamaicense (Anacardiaceae)

Leonti, Marco und Heilmann, Jörg und Heinrich, Michael und Sticher, Otto (2004) Bioactive natural products from the Popoluca Indian medicinal plant Mosquitoxylum jamaicense (Anacardiaceae). Revista latinoamericana de química 32 (3), S. 87-94.

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Zusammenfassung

In the traditional medicine of the Sierra Popoluca (Veracruz, Mexico) a decoction of the bark of Mosquitoxylum jamaicense (Anacardiaceae) is used to treat menstrual problems and gonorrhea. Both, the non-polar as well as the polar ext. showed significant cytotoxicity against KB cells in vitro. The fractionation and isolation process resulted in non-cytotoxic trans-anacardic acid, a new but ...

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Dokumentenart:Artikel
Datum:2004
Zusätzliche Informationen (Öffentlich):CAN 142:403366 1-1 Pharmacology 38681-23-1P Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than 2,3-trans-3-methoxyfustin in KB cell line); 83-46-5P (beta -Sitosterol); 99-24-1P (Methyl gallate); 480-18-2P ((+)-Taxifolin); 514-47-6P (Euphol); 444573-46-0P Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than Me gallate in KB cell line); 14351-29-2P (Dammarenediol II) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol in KB cell line); 487-52-5P (Butein) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line); 120-05-8P (Sulfuretin) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than sulfuretin in KB cell line)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
2005:243324Andere
Stichwörter / Keywords:Anacardiaceae Cytotoxicity Mass spectra (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line) Natural products Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytot NMR (carbon-13 butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line) mosquitoxylum jamaicense ext cytotoxicity
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Nein
Eingebracht am:18 Okt 2010 12:40
Zuletzt geändert:18 Okt 2010 12:40
Dokumenten-ID:17221
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