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Bioactive natural products from the Popoluca Indian medicinal plant Mosquitoxylum jamaicense (Anacardiaceae)

Leonti, Marco and Heilmann, Jörg and Heinrich, Michael and Sticher, Otto (2004) Bioactive natural products from the Popoluca Indian medicinal plant Mosquitoxylum jamaicense (Anacardiaceae). Revista latinoamericana de química 32 (3), pp. 87-94.

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Abstract

In the traditional medicine of the Sierra Popoluca (Veracruz, Mexico) a decoction of the bark of Mosquitoxylum jamaicense (Anacardiaceae) is used to treat menstrual problems and gonorrhea. Both, the non-polar as well as the polar ext. showed significant cytotoxicity against KB cells in vitro. The fractionation and isolation process resulted in non-cytotoxic trans-anacardic acid, a new but ...

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Item Type:Article
Date:2004
Additional information (public):CAN 142:403366 1-1 Pharmacology 38681-23-1P Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than 2,3-trans-3-methoxyfustin in KB cell line); 83-46-5P (beta -Sitosterol); 99-24-1P (Methyl gallate); 480-18-2P ((+)-Taxifolin); 514-47-6P (Euphol); 444573-46-0P Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than Me gallate in KB cell line); 14351-29-2P (Dammarenediol II) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol in KB cell line); 487-52-5P (Butein) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line); 120-05-8P (Sulfuretin) Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than sulfuretin in KB cell line)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Identification Number:
ValueType
2005:243324Other
Keywords:Anacardiaceae Cytotoxicity Mass spectra (butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line) Natural products Role: NPO (Natural product occurrence), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (butein from mosquitoxylum jamaicense ext. showed strongest cytot NMR (carbon-13 butein from mosquitoxylum jamaicense ext. showed strongest cytotoxic activity than dammarenediol, 2,3-trans-3-methoxyfustin, Me gallate, sulfuretin in KB cell line) mosquitoxylum jamaicense ext cytotoxicity
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Prof. Dr. Joerg Heilmann
Deposited On:18 Oct 2010 12:40
Last Modified:18 Oct 2010 12:40
Item ID:17221
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