Papaioannou, Paraskevi and Lazari, Diamanto and Karioti, Anastasia and Souleles, Christos and Heilmann, Jörg and Hadjipavlou-Litina, Dimitra and Skaltsa, Helen (2007) Phenolic compounds with antioxidant activity from Anthemis tinctoria L. (Asteraceae). Zeitschrift für Naturforschung: Section C, A journal of biosciences 62 (5/6), pp. 326-330.
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From the aerial parts of Anthemis tinctoria L. subsp. tinctoria var. pallida DC. (Asteraceae), one new cyclitol glucoside, conduritol F-1-O-(6'-O-E-p-caffeoyl)-beta -D-glucopyranoside (1), has been isolated together with four flavonoids, nicotiflorin (2), isoquercitrin (3), rutin (4) and patulitrin (5). The structures of the isolated compds. were established by means of NMR, MS, and UV spectral analyses. Methanolic ext. and pure isolated compds. were examd. for their free radical, scavenging activity, using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free stable radical, and for their inhibitory activity toward soybean lipoxygenase, using linoleic acid as substrate. Compds. 1 and 5 showed a strong scavenging effect in the DPPH radical assay. In addn. 5 also exhibited high inhibitory activity on soybean lipoxygenase.
|Additional information (public):||CAN 147:134190 1-12 Pharmacology 153-18-4 (Rutin); 526-87-4 (Conduritol); 17650-84-9 (Nicotiflorin); 19833-25-1 (Patulitrin); 21637-25-2 (Isoquercitrin) Role: NPO (Natural product occurrence), PAC (Pharmacological activity), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), USES (Uses) (phenolic compds. with antioxidant activity from Anthemis tinctoria L. (Asteraceae)|
|Institutions:||Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)|
|Keywords:||Anthemis tinctoria tinctoria Antioxidants Structure-activity relationship (phenolic compds. with antioxidant activity from Anthemis tinctoria L. (Asteraceae) phenolic antioxidant Anthemis tinctoria Asteraceae|
|Subjects:||500 Science > 570 Life sciences|
500 Science > 540 Chemistry & allied sciences
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Owner:||Prof. Dr. Joerg Heilmann|
|Deposited On:||18 Oct 2010 13:22|
|Last Modified:||18 Oct 2010 13:22|