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(1,2-Diaryl-1,2-ethylenediamine)platinum(II) complexes with sulfato and 3-sulfopropionato leaving groups: investigations with different types of coordination in the solid state, in solution and reactions with nucleophiles

Müller, Richard und Bednarski, Patrick J. und Schönenberger, Helmut (1992) (1,2-Diaryl-1,2-ethylenediamine)platinum(II) complexes with sulfato and 3-sulfopropionato leaving groups: investigations with different types of coordination in the solid state, in solution and reactions with nucleophiles. Inorganica chimica acta 195 (1), S. 77-87.

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Zusammenfassung

The syntheses, solid state and soln. chem., and the in vitro cytotoxic activities of H2O sol. (1,2-diaryl-1,2-ethylenediamine)platinum(II) complexes, having either the sulfato or the novel sulfopropionato anionic leaving group, are described. The compds. were prepd. by allowing the (1,2-diaryl-1,2-ethylenediamine)diiodoplatinum(II) complexes and either Ag2SO4 or Ag sulfopropionate to react in ...

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Dokumentenart:Artikel
Datum:1992
Zusätzliche Informationen (Öffentlich):CAN 117:203879 78-7 Inorganic Chemicals and Reactions 143988-12-9P Role: PREP (Preparation) (formation of racemic, from bis(fluorophenyl)ethylenediamine sulfato complex in DMSO); 125948-92-7P Role: PREP (Preparation) (formation of racemic, from bis(fluorophenyl)ethylenediamine sulfato complex in aq. soln.); 143988-11-8P; 143989-42-8P Role: FORM (Formation, nonpreparative), PREP (Preparation) (formation of, from bis(fluorophenyl)ethylenediamine sulfato complex in DMSO); 61951-01-7P; 62048-57-1P; 143989-39-3P Role: FORM (Formation, nonpreparative), PREP (Preparation) (formation of, from bis(fluorophenyl)ethylenediamine sulfato complex in aq. soln.); 143989-43-9P Role: FORM (Formation, nonpreparative), PREP (Preparation) (formation of, from bis(fluorophenyl)ethylenediamine sulfopropionato complex in soln.); 143988-09-4P Role: FORM (Formation, nonpreparative), PREP (Preparation) (formation of, from bis(hydroxyphenyl)ethylenediamine sulfato complex and chloride); 138258-84-1P Role: FORM (Formation, nonpreparative), PREP (Preparation) (formation of, from bis(hydroxyphenyl)ethylenediamine sulfato or sulfopropionato complex and chloride); 143989-46-2P Role: FORM (Formation, nonpreparative), PREP (Preparation) (formation of, from bis(hydroxyphenyl)ethylenediamine sulfopropionato complex and chloride); 143989-44-0P; 143989-45-1P; 144012-63-5P; 144012-64-6P Role: FORM (Formation, nonpreparative), PREP (Preparation) (formation of, from bis(hydroxyphenyl)ethylenediamine sulfopropionato complex in soln.); 143982-84-7P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and complexation of, with platinum arylethylenediamine complexes); 143989-38-2P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reaction of, with sulfopropionate); 143989-40-6P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and soln. chem. and antitumor activity of racemic); 143989-39-3P; 143989-44-0P Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (prepn. and soln. chem. and reaction with chloride and antitumor activity of); 125949-84-0 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of racemic, with sulfopropionate); 5961-88-6 (3-Sulfopropionic acid anhydride) Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with barium carbonate and silver sulfate); 14708-56-6 (Dipotassium tetraiodoplatinate(2-) Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with bis(hydroxyphenyl)ethylenediamine); 10294-26-5 (Disilver sulfate) Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with sulfopropionic acid anhydride-barium carbonate rx product); 143989-41-7 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (soln. chem. and antitumor activity of racemic)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Entpflichtete oder im Ruhestand befindliche Professoren > Prof. Schönenberger
Projekte:SFB 234
Identifikationsnummer:
WertTyp
1992:603879Andere
Stichwörter / Keywords:Neoplasm inhibitors (mammary gland carcinoma, platinum sulfato or sulfopropionato complexes with diarylethylenediamines) Mammary gland (neoplasm, carcinoma, inhibitors, platinum sulfato or sulfopropionato complexes with diarylethylenediamines) antitumor agent platinum ethylenediamine sulfopropionato sulfato
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Ja
Eingebracht am:12 Nov 2010 06:58
Zuletzt geändert:12 Nov 2010 06:58
Dokumenten-ID:17694
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