Ruckdeschel, G. and Stransky, D. and Schönenberger, Helmut (1977) Antimycobacterial properties of N-alkylbenzylamines. Pharmazie 32 (2), pp. 119-122.
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Abstract
A no. of N-alkylbenzylamines were tested for antimycobacterial activity against various strains of Mycobacterium, as were many commonly used tuberculostatics. N-butyl-3-fluorobenzylamine (I) [60509-34-4] was the most active of the alkylbenzylamines, but pronounced inhibitory activity was also shown by N-butylbenzylamines with 3-chloro, 3-iodo, 3-nitro, or 4-dimethylamino substituents.
| Item Type: | Article | ||||
|---|---|---|---|---|---|
| Additional information (public): | CAN 86:150969 3-2 Biochemical Interactions 54-85-3; 57-92-1; 65-49-6; 68-41-7; 74-55-5; 100-46-9; 100-46-9D; 103-67-3; 104-06-3; 536-33-4; 910-86-1; 1667-16-9; 1687-68-9; 2032-33-9; 2403-22-7; 4462-17-3; 8063-07-8; 11003-38-6; 13292-46-1; 14222-60-7; 16183-21-4; 16183-28-1; 16183-35-0; 25468-43-3; 32988-50-4; 42882-36-0; 60508-94-3; 60508-95-4; 60509-33-3; 60509-34-4; 60509-38-8; 60509-39-9; 60509-40-2; 60509-41-3; 60509-42-4; 60509-43-5; 60509-45-7; 60509-46-8; 60509-48-0; 60509-49-1; 60509-54-8; 60509-76-4; 62498-73-1; 62498-74-2; 62498-75-3 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (Mycobacterium sensitivity to) | ||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger | ||||
| Identification Number: |
| ||||
| Keywords: | Tuberculostatics (N-alkylbenzylamines) Mycobacterium (N-alkylbenzylamines sensitivity of) Molecular structure-biological activity relationship (tuberculostatic, of N-alkylbenzylamines) benzylamine deriv Mycobacterium inhibition tuberculostat benzylamine deriv | ||||
| Subjects: | 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Unknown | ||||
| Owner: | Petra Gürster | ||||
| Deposited On: | 22 Nov 2010 13:14 | ||||
| Last Modified: | 22 Nov 2010 13:14 | ||||
| Item ID: | 18129 |
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