Cytostatic compounds. VII. Effect of aldimine structure on the N,N'-dialkyl-alpha ,alpha '-diphenylethylenediamine-benzylalkylamine ratio formed in the reduction of benzylidenealkylamines with activated aluminum

Abstract

cf. CA 67: 21262k. The formation of the dimeric redn. product was found to be affected by the stability of the intermediate radical which is related to the number of possible mesomeric structures of the aldimine (Schiff's base) and to the concn. of the reaction soln. [TABLE OMITTED] The observed reaction route (% dimer formed) by redn. of 0.025 mole Schiff base with 0.075 mole Al and 200 mg. HgCl2 in 100 ml. and 25 ml. EtOH is shown in the 1st table. Yields and phys. properties are given in the 2nd table. [TABLE OMITTED]