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Regulation of integrin activity by MIA

Bauer, Richard and Humphries, Martin and Fässler, Reinhard and Winklmeier, Andreas and Craig, Sue E and Bosserhoff, Anja-Katrin (2006) Regulation of integrin activity by MIA. The Journal of biological chemistry 281 (17), pp. 11669-11677.

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Other URL: http://dx.doi.org/10.1074/jbc.M511367200


Abstract

MIA (melanoma inhibitory activity) has been identified as a small protein secreted from malignant melanoma cells, which interacts with extracellular matrix proteins including fibronectin. Here, we show that MIA negatively regulates the activity of the mitogen-activated protein kinase pathway in malignant melanoma. Using far Western blotting and co-immunoprecipitation we searched for MIA-binding ...

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Item Type:Article
Date:28 April 2006
Institutions:Medicine > Lehrstuhl für Dermatologie und Venerologie
Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
16517605PubMed ID
10.1074/jbc.M511367200DOI
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:29 Mar 2007
Last Modified:13 Mar 2014 10:10
Item ID:1941
Owner Only: item control page

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