Tzankov, Alexandar and Gschwendtner, Andreas and Augustin, Florian and Fiegl, Michael and Obermann, Ellen C. and Dirnhofer, Stephan and Went, Philip (2006) Diffuse large B-cell lymphoma with overexpression of cyclin e substantiates poor standard treatment response and inferior outcome. Clinical cancer research : an official journal of the American Association for Cancer Research 12 (7 Pt 1), pp. 2125-2132.
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PURPOSE: Gold standard to predict survival and stratify patients for risk-adapted therapy in diffuse large B-cell lymphoma (DLBCL) is the international prognostic index, although it does not consider the molecular heterogeneity of DLBCL. Deregulation of cyclin E (CCNE) is a strong predictor of poor prognosis in some neoplastic diseases. In tumor cells, it induces chromosomal instability with an ...
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|Date:||1 April 2006|
|Institutions:||Medicine > Lehrstuhl für Pathologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||29 Mar 2007|
|Last Modified:||13 Mar 2014 10:10|