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Identification of a region in the Pr55gag-polyprotein essential for HIV-1 particle formation

von Poblotzki, A. and Wagner, Ralf and Niedrig, M. and Wanner, G. and Wolf, Hans J. and Modrow, Susanne (1993) Identification of a region in the Pr55gag-polyprotein essential for HIV-1 particle formation. Virology 193 (2), pp. 981-985.

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Abstract

The pr55gag polyprotein of HIV-1 plays a critical role in the formation of immature virus particles in the cell and during the budding process. We investigated the influence of amino acid substitutions in the p24CA- region of the gag polyprotein on the viral assembly process. Deletion of the amino acids 341-352 in the carboxy terminal part of the p24CA resulted in a loss of the capacity of the ...

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Item Type:Article
Date:1993
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
8460500PubMed ID
10.1006/viro.1993.1210DOI
Classification:
NotationType
Amino Acid SequenceMESH
Base SequenceMESH
Cell LineMESH
Codon/geneticsMESH
Gene Products, gag/metabolismMESH
HIV-1/physiologyMESH
HIV-2/physiologyMESH
HumansMESH
Molecular Sequence DataMESH
Polymerase Chain Reaction/methodsMESH
Protein Precursors/metabolismMESH
Restriction MappingMESH
Sequence Homology, Amino AcidMESH
Vaccinia virus/geneticsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:07 Apr 2011 06:43
Last Modified:13 Mar 2014 17:11
Item ID:20408
Owner Only: item control page

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