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Expression of the Epstein-Barr virus 138-kDa early protein in Escherichia coli for the use as antigen in diagnostic tests

Motz, M. and Fan, J. and Seibl, R. and Jilg, Wolfgang and Wolf, Hans J. (1986) Expression of the Epstein-Barr virus 138-kDa early protein in Escherichia coli for the use as antigen in diagnostic tests. Gene 42 (3), pp. 303-312.

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Abstract

We have attempted to produce the 138-kDa early protein (ep 138) of Epstein-Barr virus (EBV) in Escherichia coli. This protein was found, by immunoprecipitation, to be a clinically relevant antigen, especially for the determination of the IgA-titer in patients with nasopharyngeal carcinoma (NPC). Since the expression of the entire ep 138 coding region was unsuccessful, we synthesized only the ...

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Item Type:Article
Date:1986
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
2426158PubMed ID
10.1016/0378-1119(86)90234-9 DOI
Classification:
NotationType
Antigens, Viral/geneticsMESH
Cloning, MolecularMESH
DNA-Binding Proteins/geneticsMESH
EpitopesMESH
Gene Expression RegulationMESH
GenesMESH
Genes, ViralMESH
Genetic Engineering/methodsMESH
Herpesvirus 4, Human/immunologyMESH
Protein ConformationMESH
Recombinant Proteins/geneticsMESH
SolubilityMESH
Viral Proteins/geneticsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:20 Apr 2011 12:37
Last Modified:13 Mar 2014 17:17
Item ID:20586
Owner Only: item control page
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