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Tumor necrosis factor mediates endotoxic effects in mice

Bauss, F. and Dröge, W. and Männel, Daniela N. (1987) Tumor necrosis factor mediates endotoxic effects in mice. Infection and immunity 55 (7), pp. 1622-1625.

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Abstract

Endotoxic reactions induced in mice by recombinant human tumor necrosis factor (TNF) were examined. Mice showed a dose-dependent hypothermia after intravenous TNF injection which was similar to a reaction to lipopolysaccharide injection. Plasma glucose levels were decreased, and plasma lactate levels were increased. Blood hematocrit levels were increased after TNF injection. No interleukin-1 ...

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Item Type:Article
Date:1987
Institutions:Medicine > Lehrstuhl für Immunologie
Identification Number:
ValueType
3863119PubMed ID
Classification:
NotationType
AnimalsMESH
Blood Cell CountMESH
Blood Glucose/metabolismMESH
Body Temperature Regulation/drug effectsMESH
Endotoxins/toxicityMESH
Glycoproteins/toxicityMESH
HematocritMESH
Lactates/bloodMESH
Lipopolysaccharides/toxicityMESH
MaleMESH
MiceMESH
Mice, Inbred C3HMESH
SalmonellaMESH
Tumor Necrosis Factor-alphaMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:22 Jun 2011 08:11
Last Modified:13 Mar 2014 17:35
Item ID:21185
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