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Biological aspects of tumor necrosis factor

Männel, Daniela N. (1986) Biological aspects of tumor necrosis factor. Immunobiology 172 (3-5), pp. 283-290.

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Abstract

Tumor necrosis factor (TNF) has been determined as an endogenous mediator for endotoxin-induced tumor necrosis. This macrophage product has been biochemically characterized and its protein structure defined by molecular cloning of the TNF gene. Experiments with antibodies to TNF demonstrated that TNF acts as an effector molecule of activated cytotoxic macrophages involved in tumor destruction. ...

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Item Type:Article
Date:1986
Institutions:Medicine > Lehrstuhl für Immunologie
Identification Number:
ValueType
3100430PubMed ID
Classification:
NotationType
AnimalsMESH
Body Temperature/drug effectsMESH
Cell Survival/drug effectsMESH
Cells, CulturedMESH
Endotoxins/toxicityMESH
FemaleMESH
Glycoproteins/pharmacologyMESH
Interferon-gamma/pharmacologyMESH
Macrophage ActivationMESH
Macrophages/physiologyMESH
MaleMESH
MiceMESH
Neoplasms, Experimental/therapyMESH
Recombinant Proteins/pharmacologyMESH
Tumor Necrosis Factor-alphaMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:22 Jun 2011 09:24
Last Modified:13 Mar 2014 17:40
Item ID:21190
Owner Only: item control page
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