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Incidence and clinical importance of perioperative histamine release: randomised study of volume loading and antihistamines after induction of anaesthesia

Lorenz, Wilfried and Duda, D. and Dick, W. and Sitter, H. and Doenicke, A. and Black, A. and Weber, Doris and Menke, H. and Stinner, B. and Junginger, T. and Trial Group, Mainz/Marburg (1994) Incidence and clinical importance of perioperative histamine release: randomised study of volume loading and antihistamines after induction of anaesthesia. Lancet (London) 343 (8903), pp. 933-940.

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Abstract

Although histamine release is recognised as a common event during anaesthesia and surgery, few clinicians judge the resultant cardiorespiratory disturbances serious enough to warrant prophylaxis with antihistamines. We have assessed the incidence and importance of histamine release in a randomised 2 x 2 factorial study. 240 patients representing a routine throughput of major general surgery were ...

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Item Type:Article
Date:1994
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:
ValueType
7519707PubMed ID
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
Aged, 80 and overMESH
Anesthesia, GeneralMESH
Cimetidine/therapeutic useMESH
Dimethindene/therapeutic useMESH
Double-Blind MethodMESH
FemaleMESH
Hemodynamics/drug effectsMESH
Histamine/bloodMESH
Histamine Release/drug effectsMESH
HumansMESH
Intraoperative Complications/prevention & controlMESH
MaleMESH
Middle AgedMESH
Polygeline/therapeutic useMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:16 Aug 2011 12:01
Last Modified:13 Mar 2014 17:49
Item ID:21752
Owner Only: item control page
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