Hagemann, Carsten and Anacker, Jelena and Haas, Stefanie and Riesner, Daniela and Schömig, Beate and Ernestus, Ralf-Ingo and Vince, Giles H.
Comparative expression pattern of Matrix-Metalloproteinases in human glioblastoma cell-lines and primary cultures.
BMC research notes 3, p. 293.
Literature-data and our own results suggest that the expression pattern of MMPs is highly variable, dependent on the cell-line and the cell-culture conditions used and that also regulation of MMP expression by cytokines is cell-line dependent. This is of high impact for the transfer of cell-culture experiments to clinical implementation.