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Increasing capillary diameter and the incorporation of gelatin enhance axon outgrowth in alginate-based anisotropic hydrogels

Pawara, Kiran and Mueller, Rainer and Caioni, Massimiliano and Prang, Peter and Bogdan, Ulrich and Kunz, Werner and Weidner, Norbert (2011) Increasing capillary diameter and the incorporation of gelatin enhance axon outgrowth in alginate-based anisotropic hydrogels. Acta Biomaterialia 7 (7), pp. 2826-2834.

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Abstract

Substantial recovery of function following peripheral and central nervous system (CNS) injury critically depends on longitudinally directed axon regeneration across the injury site, which requires a mech. guidance providing scaffold. We have previously shown that anisotropic alginate-based hydrogels with a defined capillary diam. (25 μm), which form via a self-organizing process driven by ...

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Item Type:Article
Date:2011
Institutions:Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry) > Prof. Dr. Werner Kunz
Identification Number:
ValueType
10.1016/j.actbio.2011.04.006DOI
CODEN:ABCICBOther
Keywords:capillary diam anisotropy Manugel DJX axon outgrowth Schwann cell gelatin hydrogel dorsal root ganglion
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Georg Berger
Deposited On:09 May 2012 11:18
Last Modified:09 May 2012 11:18
Item ID:24278
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