Reichenbach-Klinke, R. and Kruppa, M. and König, B. (2002) NADH Model Systems functionalized with Zn(II)-cyclen as Flavin Binding Site Structure Dependence of the Redox Reaction within reversible Aggregates. J. Am. Chem. Soc. 124, 12999 - 13007.
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The relative positions and conformations of the prosthetic group FAD and the cofactor NADH have been remarkably conserved within the structurally diverse group of flavin enzymes. To provide a chemical rational for such an obviously optimal relative disposition of the redox partners for efficient reaction we have synthesized NADH models with Zn(II)-cyclen substituents for reversible flavin binding ...
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|Institutions:||Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König|
|Subjects:||500 Science > 540 Chemistry & allied sciences|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||05 Mar 2009 10:54|
|Last Modified:||15 Jul 2011 08:44|