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New heterocyclic β-sheet ligands with peptidic recognition elements

Rzepecki, P. and Gallmeier, H. and Geib, N. and König, B. and Schrader, T. (2004) New heterocyclic β-sheet ligands with peptidic recognition elements. J. Org. Chem. 69, 5168 – 5178.

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Abstract

A detailed and comprehensive overview is presented about the design, modeling, and synthesis, as well as spectroscopic characterization, of a new class of beta-sheet ligands. The characteristic feature of these compounds is a peptidic chimeric structure formed from a specific combination of aminopyrazolecarboxylic acids with naturally occurring alpha-amino acids. These hybrid peptides are ...

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Item Type:Article
Date:2004
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.1021/jo0496603DOI
15287758 PubMed ID
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:05 Mar 2009 10:54
Last Modified:09 Nov 2010 13:24
Item ID:6244
Owner Only: item control page
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