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Enantio- and Diastereoselective Syntheses of Cyclic Cα-Tetrasubstituted α-Amino Acids and Their Use to Induce Stable Conformations in Short Peptides (Review)

Maity, P. and König, Burkhard (2007) Enantio- and Diastereoselective Syntheses of Cyclic Cα-Tetrasubstituted α-Amino Acids and Their Use to Induce Stable Conformations in Short Peptides (Review). Pept. Sci. 90, 8 - 27.

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Abstract

Cα-Tetrasubstituted α-amino acids are widely used to design and prepare peptides and peptide mimics with constrained conformations. Subcategories of these compounds are cyclic Cα-tetrasubstituted α-amino acids, in which both α-substituents are covalently connected. This survey presents recent advances in the synthesis and application of cyclic Cα-tetrasubstituted α-amino acids in a systematic ...

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Item Type:Article
Date:2007
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.1002/bip.20902DOI
Keywords:artificial amino acids; cyclic compounds; synthesis; conformation
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:05 Mar 2009 10:55
Last Modified:03 Feb 2014 11:29
Item ID:6286
Owner Only: item control page
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