Different effects of adiponectin isoforms in human monocytic cells

DOI zum Zitieren dieses Dokuments:: 10.5283/epub.1003

Neumeier, Markus ; Weigert, Johanna ; Schäffler, Andreas ; Wehrwein, Gabriele ; Müller-Ladner, Ulf ; Schölmerich, Jürgen ; Wrede, Christian ; Buechler, Christa

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Veröffentlichungsdatum dieses Volltextes: 05 Aug 2009 13:24

Alternative Links zum Volltext:DOI Pubmed Verlag

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Zusammenfassung

Adiponectin (APM) is an adipocyte-derived adipokine with immunosuppressive, antidiabetic, and antiatherosclerotic properties. Low molecular weight (LMW)- and higher molecular weight (HMW)-APM circulate in the serum and activate different signaling pathways. We were interested to see whether LMW-APM exerts different effects on monocytic cells compared with the HMW isoform. Therefore, the effects ...